Pain and fever are common ailments that can disrupt daily life, whether caused by a headache, muscle ache, or an infection. Paracetamol, also known as acetaminophen, is one of the most widely used medications globally for relieving pain and reducing fever. Its safety, efficacy, and accessibility make it a staple in households and healthcare settings.
Aingo Pharma’s Paracetamol 650 mg Tablets are designed to provide fast, reliable relief from moderate pain and fever, catering to adults and adolescents with a higher dose than standard 500 mg tablets. This blog offers a detailed exploration of paracetamol’s composition, mechanism of action, therapeutic uses, dosage guidelines, safety profile, and unique benefits, with a focus on why Aingo Pharma’s formulation stands out in the market.
With pain and fever being prevalent concerns, particularly in India due to seasonal infections and lifestyle-related conditions, understanding paracetamol’s role is essential. This guide aims to empower readers with knowledge to use paracetamol safely and effectively, ensuring optimal health outcomes.
Paracetamol(C8H9NO2) is a non-opioid analgesic and antipyretic medication used to relieve mild to moderate pain and reduce fever. It is a first-line treatment for conditions like headaches, muscle aches, menstrual cramps, toothaches, and fever associated with infections. Unlike non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen, paracetamol has minimal anti-inflammatory effects, making it ideal for pain and fever without gastrointestinal irritation.
Aingo Pharma’s Paracetamol 650 mg IP Tablets (Aincol-650) offer a higher dose for enhanced efficacy in adults, ensuring rapid symptom relief with a single tablet. These tablets are particularly valuable for managing acute pain and fever episodes in busy lifestyles.
The composition of paracetamol tablets determines their efficacy, safety, and tolerability. The active ingredient (paracetamol) provides the therapeutic effect, while inactive ingredients (excipients) ensure the tablet’s stability, dissolution, and absorption. Knowing these components helps patients and healthcare providers assess potential allergies, interactions, and suitability for specific conditions.
Aingo Pharma prioritizes high-quality formulations, using excipients that enhance bioavailability and minimize adverse effects. By understanding paracetamol’s composition, users can confidently incorporate it into their symptom management plan, ensuring safe and effective relief.
Aingo Pharma’s Paracetamol 650 mg Tablets include carefully selected excipients to optimize delivery and stability:
These excipients are generally recognized as safe (GRAS) and used in minimal quantities to avoid side effects. Aingo Pharma’s formulation avoids unnecessary additives, making it suitable for patients with sensitivities.
Paracetamol’s exact mechanism is not fully elucidated, but it primarily acts in the central nervous system:
Paracetamol’s rapid onset (within 30–60 minutes) and duration of action (4–6 hours) make it ideal for acute symptom relief. Aingo Pharma’s 650 mg tablets ensure a higher peak plasma concentration, enhancing efficacy for moderate pain.
Role of Ingredients in Treatment
Aingo Pharma’s formulation optimizes absorption, ensuring consistent plasma levels for effective symptom control.
Paracetamol 650 mg is indicated for:
The following table outlines dosage recommendations for Aingo Pharma’s Paracetamol 650 mg Tablets:
| Condition | Dosage | Frequency | Maximum Daily Dose | Administration Notes |
| Pain (Adults/Adolescents >12) | 650 mg | Every 4–6 hours | 4 g (4000 mg; ~6 tablets) | Take with water; avoid exceeding 4 g/day |
| Fever (Adults/Adolescents >12) | 650 mg | Every 4–6 hours | 4 g (4000 mg) | Monitor temperature; hydrate well |
| Pediatric (6–12 years) | 325 mg (half tablet) | Every 4–6 hours | 10–15 mg/kg/dose, max 2.6 g/day | Consult pediatrician; use with caution |
| Elderly | 650 mg | Every 4–6 hours | 3–4 g/day | Monitor liver/renal function |
Source: Adapted from WebMD, Mayo Clinic, and Indian Pharmacopoeia
The 650 mg strength reduces the number of tablets needed compared to 500 mg, improving compliance. Excipients like sodium starch glycolate ensure rapid dissolution, supporting consistent dosing intervals.
Paracetamol is one of the safest medications when used as directed, but precautions are critical to avoid toxicity:
Rare, but may include:
Aingo Pharma’s hypoallergenic excipients minimize allergic risks.
Potential Side Effects
Paracetamol has a low side effect profile when used correctly:
| Frequency | Side Effect | Management |
| Common | Nausea, rash (mild) | Usually self-limiting; consult if persistent |
| Rare | Hepatotoxicity (overdose), blood disorders (e.g., thrombocytopenia) | Seek emergency care for overdose symptoms |
| Very Rare | Anaphylaxis, Stevens-Johnson syndrome | Discontinue; seek immediate medical attention |
Paracetamol has minimal interactions due to its non-CYP450 metabolism:
| Drug Class | Interaction | Recommendation |
| Alcohol | Increases NAPQI, raising liver toxicity risk | Avoid alcohol during therapy |
| Warfarin | May enhance anticoagulant effect (high doses) | Monitor INR if prolonged use |
| Carbamazepine, Phenytoin | Induce CYP2E1, increasing NAPQI production | Use lowest effective dose |
| Isoniazid | Depletes glutathione, raising toxicity risk | Monitor liver function |
| Metoclopramide | Speeds gastric emptying, hastening absorption | No adjustment needed |
Aingo Pharma’s tablets are designed for consistent release, reducing interaction variability.
Aingo Pharma’s 650 mg tablets use advanced excipients like sodium starch glycolate for rapid dissolution, ensuring faster onset compared to standard generics. The 650 mg dose reduces tablet burden, enhancing patient compliance.
| Feature | Aingo Pharma Paracetamol | Ibuprofen (NSAID) | Aspirin (NSAID) | Naproxen (NSAID) |
| Class | Analgesic/Antipyretic | NSAID | NSAID | NSAID |
| Pain Relief | Mild to moderate | Mild to moderate | Mild to moderate | Moderate |
| Anti-Inflammatory | None | Yes | Yes | Yes |
| GI Risk | Low | High | High | Moderate |
| Cardiovascular Risk | None | Moderate | High (high doses) | Moderate |
| Liver Risk | High (overdose) | Low | Low | Low |
| Dosing Frequency | Every 4–6 hours | Every 6–8 hours | Every 4–6 hours | Every 8–12 hours |
| Cost | Cost-effective | Moderate | Low | Moderate |
| Aingo Pharma Advantage | Rapid dissolution, 650 mg dose | N/A | N/A | N/A |
Generic paracetamol contains the same active ingredient as branded versions (e.g., Crocin, Tylenol), but excipients may differ, affecting dissolution. Aingo Pharma’s generics ensure bioequivalence with superior formulation for reliable efficacy.
Alternative Therapies
Aingo Pharma’s Paracetamol 650 mg Tablets excel in the market for several reasons:
Aingo Pharma’s commitment to quality and affordability ensures that its paracetamol tablets deliver superior outcomes, making them the preferred choice for symptom relief.
Paracetamol offers a wide range of benefits for pain and fever management:
To optimize the benefits of Aingo Pharma’s Paracetamol 650 mg Tablets, follow these guidelines:
Paracetamol 650 mg is commonly used to reduce fever and relieve mild to moderate pain, such as headaches, body aches, menstrual cramps, back pain, toothaches, and arthritis-related discomfort.
Yes, Paracetamol 650 mg can be taken with or without food. However, if you have a sensitive stomach, taking it with food or milk may help prevent discomfort.
The usual adult dose is 650 mg every 4 to 6 hours as needed. Do not exceed 4,000 mg (4 g) in 24 hours to avoid the risk of liver damage.
Paracetamol 650 mg is generally not recommended for children under 12 years. Pediatric formulations or adjusted dosages should be used under a doctor’s supervision.
Yes, Paracetamol is considered safe during pregnancy when taken at recommended doses. Always consult a doctor before long-term or frequent use during pregnancy.
Paracetamol is safe with many medications but may interact with drugs like warfarin or certain anti-epileptics. Always inform your doctor or pharmacist about all medicines you’re taking.
Side effects are rare but may include nausea, rash, or allergic reactions. Serious liver damage can occur if taken in excessive doses or with alcohol.
Seek emergency medical help immediately. Symptoms may not appear for 24–48 hours and may include nausea, vomiting, abdominal pain, and yellowing of the skin or eyes (jaundice).
No, it’s strongly advised to avoid alcohol while using Paracetamol as it increases the risk of liver toxicity.
Swallow the tablet whole with water. Only crush or split it if advised by your doctor, as altering the form may affect its effectiveness.
| Aspect | Details |
| Active Ingredient | Paracetamol 650 mg |
| Indications | Mild to moderate pain, fever |
| Dosage | 650 mg every 4–6 hours, max 4 g/day |
| Administration | Oral, with/without food, as needed |
| Side Effects | Rare: nausea, rash; overdose: hepatotoxicity |
| Interactions | Alcohol, warfarin, CYP2E1 inducers; monitor as needed |
| Aingo Pharma Advantage | Rapid dissolution, 650 mg dose, GMP quality, cost-effective |
Paracetamol 650 mg is a cornerstone of pain and fever management, offering fast, safe, and effective relief for a wide range of conditions. Its non-sedating, low-risk profile makes it a preferred choice for adults and adolescents seeking to maintain daily productivity. Aingo Pharma’s Paracetamol 650 mg Tablets elevate this therapy with their high-potency dose, advanced formulation, and rigorous quality standards, ensuring rapid symptom relief and patient satisfaction.
By combining innovation with affordability, Aingo Pharma provides a trusted solution for India’s diverse healthcare needs, from seasonal fevers to chronic pain. For those seeking reliable relief, Aingo Pharma’s paracetamol tablets are the ideal partner in achieving comfort and well-being.
