Klith‑125 is a pediatric formulation of Clarithromycin, a macrolide antibiotic, available in a sweet, fruit-flavored oral suspension. Each 5 mL contains 125 mg of Clarithromycin. It is designed specifically for children aged 6 months to 12 years.
✅ Indications
Klith‑125 is used to treat bacterial infections in children, including:
– Respiratory tract infections (such as pharyngitis, sinusitis, bronchitis, and pneumonia)
– Ear infections (otitis media)
– Skin and soft tissue infections
💊 Mechanism of Action
Clarithromycin works by binding to the 50S ribosomal subunit of bacteria, inhibiting protein synthesis and halting bacterial growth.
👶 Dosage & Administration
1. Recommended Pediatric Dosage:
~7.5 mg/kg body weight every 12 hours (twice daily) for 5–10 days.
2. Typical Weight-Based Dosing (for 125 mg/5 mL suspension):
8–11 kg: 2.5 mL twice daily
12–19 kg: 5 mL twice daily
20–29 kg: 7.5 mL twice daily
30–40 kg: 10 mL twice daily
Shake well before use.
Can be taken with or without food.
Always use the provided measuring spoon or syringe.
⚠️ Contraindications & Precautions
Avoid Klith‑125 in children with:
Allergy to macrolide antibiotics
History of QT prolongation or cardiac arrhythmias
Electrolyte imbalances (low potassium or magnesium)
Severe liver and kidney disorders
Caution is advised when used with other medications, especially those affecting heart rhythm or liver enzymes.
⚕️ Possible Side Effects
1. Common:
Nausea
Vomiting
Diarrhea
Abnormal taste
Headache
Mild skin rash
2. Rare but Serious:
Liver dysfunction
Severe allergic reactions
Irregular heartbeat
Hearing changes
Antibiotic-associated colitis
🧊 Storage Instructions
Store the reconstituted suspension at room temperature (below 25 °C).
Do not refrigerate.
Discard any unused suspension after 14 days.
🧂 Formulation Highlights
Sugar-based suspension with a palatable fruit flavor
Contains sucrose and aspartame for improved taste
Not recommended for children with certain sugar intolerances or phenylketonuria
