LETROGO 2.5 Letrozole Tablets IP contain the active ingredient letrozole, which belongs to the class of medicines known as aromatase inhibitors. This medication is primarily used as an anti-cancer therapy for postmenopausal women with hormone receptor-positive breast cancer. It may be prescribed as a first-line treatment or as supportive therapy after other main treatments such as surgery or radiation.
Mechanism of Action:
Letrozole works by blocking the aromatase enzyme, which is responsible for the production of estrogen in the body.
By lowering estrogen levels, it helps slow or stop the growth of breast cancer cells that require estrogen to grow.
Indications:
Treatment of early and advanced breast cancer in postmenopausal women whose tumors are hormone receptor-positive.
It may also be used to induce ovulation in cases of anovulatory infertility, as directed by a physician.
Dosage and Administration:
The typical dose is 2.5 mg once daily, taken with or without food.
The duration and exact dosage should be determined by a healthcare provider based on individual patient needs.
Tablets should be swallowed whole with water and not crushed or chewed.
Precautions:
Not recommended for premenopausal women or those who are pregnant or breastfeeding, as it can cause harm to a developing baby and is not effective before menopause.
Patients should inform their doctor if they have a history of liver or kidney disease, osteoporosis, or are taking other medications.
Regular monitoring of cholesterol levels and bone mineral density is advised due to potential side effects.
Common Side Effects:
Hot flashes
Fatigue
Increased sweating
Joint pain
Bone pain
High cholesterol
Nausea
Dizziness
Osteoporosis or decreased bone mineral density.
Storage:
Store at room temperature, away from moisture and heat.
Keep out of reach of children and pets.
Important Note: Use effective contraception during treatment and for at least 3 weeks after the last dose, as letrozole can harm an unborn baby
