Racole‑SB 130 Capsules contain Itraconazole IP 130 mg, a broad-spectrum triazole antifungal agent indicated for dermatophytic infections, onychomycosis, histoplasmosis, and other systemic fungal infections. Itraconazole inhibits fungal cytochrome P450 enzyme 14ɑ-demethylase, leading to disrupted ergosterol synthesis and fungal cell membrane dysfunction.
🔹 Clinical Benefits:
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Treats dermatophyte infections like tinea pedis, corporis, and cruris
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Effective in fungal nail infections (onychomycosis)
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Used for systemic fungal infections including histoplasmosis and blastomycosis (systemic dosing as per guidelines)
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High tissue penetration and less frequent dosing improve compliance
🔹 Indications:
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Cutaneous fungal infections of skin, hair, or nail
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Mucocutaneous candidiasis
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Systemic mycoses (prescribed under specialist supervision)
🔹 Dosage:
One capsule once daily for 2–4 weeks (skin infections) or up to 12 weeks (nail infections), depending on individual response and physician guidance. Take with food to enhance absorption.
🔹 Safety & Precautions:
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Monitor liver enzymes—avoid in pre-existing hepatic dysfunction
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Not recommended with cisapride, quinidine, or other QT‑prolonging drugs
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Avoid during pregnancy and breastfeeding
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May interact with statins, warfarin, or certain antihistamines
🔹 Storage:
Store at room temperature in original packaging. Keep in a cool, dry place away from children and light.
Racole‑SB 130 offers a high potency, once-daily antifungal option with proven efficacy and convenience—ideal for both superficial and systemic fungal therapy.
