ANGORAB-DSR – Rabeprazole Sodium & Domperidone Sustained-Release Capsules
ANGORAB-DSR is a prescription combination capsule containing Rabeprazole Sodium 20 mg and Domperidone 30 mg. The formulation combines an acid-suppressing proton pump inhibitor with a gastrointestinal prokinetic and antiemetic medicine. The product shown is formulated with Rabeprazole as enteric-coated pellets and Domperidone as a sustained-release component.
Rabeprazole reduces gastric acid secretion by inhibiting the gastric proton pump. Domperidone acts primarily as a dopamine receptor antagonist and can help reduce nausea and vomiting while supporting gastrointestinal motility. Because domperidone has important cardiovascular safety considerations, its use should be limited to appropriate patients and according to local prescribing guidance.
Composition (Per Hard Gelatin Capsule)
| Ingredient | Quantity |
|---|---|
| Rabeprazole Sodium I.P. | 20 mg |
| Rabeprazole Sodium | As enteric-coated pellets |
| Domperidone I.P. | 30 mg |
| Domperidone | As sustained-release component |
Pack Size: 10 × 10 Capsules
Strength: Rabeprazole Sodium 20 mg + Domperidone 30 mg
Dosage Form: Hard Gelatin Capsule
Release Type: Rabeprazole Enteric-Coated + Domperidone Sustained-Release
Category: Prescription Gastrointestinal Acid-Suppressing & Prokinetic Combination
Key Selling Points
- ✅ Combination of Rabeprazole and Domperidone in a single capsule
- ✅ Rabeprazole 20 mg provides gastric acid suppression
- ✅ Domperidone 30 mg provides antiemetic and prokinetic activity
- ✅ Rabeprazole is formulated as enteric-coated pellets
- ✅ Domperidone is formulated as a sustained-release component
- ✅ Convenient hard gelatin capsule dosage form
- ✅ Available in a practical 10 × 10 capsule pack
Benefits of ANGORAB-DSR
- Helps reduce gastric acid secretion
- Rabeprazole may help manage acid-related gastrointestinal symptoms when appropriately prescribed
- Domperidone may help relieve nausea and vomiting in appropriate clinical situations
- Supports gastrointestinal motility through the prokinetic action of Domperidone
- Combines acid suppression and gastrointestinal symptom management in one dosage form
- Enteric-coated and sustained-release formulation components are designed for their respective release characteristics
How to Take
Take ANGORAB-DSR exactly as prescribed by your doctor. Swallow the capsule whole with sufficient water. Do not crush, chew, or open the capsule unless specifically instructed by your healthcare professional because the product contains modified-release components.
Follow the prescribed dose, timing, and duration of treatment. Do not increase the dose or continue treatment for longer than recommended without medical advice. Domperidone should generally be used at the lowest effective dose for the shortest appropriate duration because of its potential cardiac risks.
Precautions
- For prescription use only.
- Do not use if you have a known allergy to Rabeprazole, Domperidone, other proton pump inhibitors, or any component of the formulation.
- Inform your doctor if you have heart disease, an abnormal heart rhythm, prolonged QT interval, significant electrolyte abnormalities, or a history of fainting or unexplained cardiac symptoms.
- Domperidone may increase the risk of QT prolongation and serious ventricular arrhythmias, particularly in susceptible patients, at higher doses, or when combined with certain interacting medicines.
- Do not use Domperidone with medicines known to prolong the QT interval or potent CYP3A4 inhibitors unless specifically directed by an appropriate healthcare professional.
- Inform your doctor if you have moderate or severe liver impairment or significant kidney disease.
- Tell your doctor about all prescription medicines, over-the-counter medicines, supplements, and herbal products you are taking.
- Use during pregnancy or breastfeeding only after consultation with a qualified healthcare professional.
- Seek urgent medical attention if you develop fainting, rapid or irregular heartbeat, severe dizziness, breathing difficulty, or other symptoms suggestive of a serious reaction.
Frequently Asked Questions (FAQs)
1. What is ANGORAB-DSR used for?
ANGORAB-DSR may be prescribed for selected gastrointestinal conditions where acid suppression and management of nausea or impaired gastrointestinal motility are considered appropriate. The exact indication should be determined by a healthcare professional based on the patient's symptoms and clinical condition.
2. What does ANGORAB-DSR contain?
Each hard gelatin capsule contains Rabeprazole Sodium 20 mg as enteric-coated pellets and Domperidone 30 mg as a sustained-release component, as shown on the product packaging.
3. How does ANGORAB-DSR work?
Rabeprazole is a proton pump inhibitor that suppresses gastric acid secretion. Domperidone blocks dopamine receptors and has antiemetic and prokinetic effects, helping reduce nausea and vomiting and supporting gastrointestinal motility.
4. Can ANGORAB-DSR be taken with other medicines?
ANGORAB-DSR may interact with other medicines, particularly because Domperidone can interact with medicines that prolong the QT interval or inhibit CYP3A4. Tell your doctor or pharmacist about all medicines and supplements you are taking before using this product.
5. Should ANGORAB-DSR be taken before or after food?
The appropriate timing depends on the prescribed product and the reason for treatment. Follow the specific instructions provided by your doctor or pharmacist rather than changing the timing yourself.
6. What are the possible side effects?
Possible side effects may include headache, dizziness, nausea, abdominal discomfort, diarrhoea, constipation, or other gastrointestinal symptoms. Domperidone can rarely cause serious cardiac effects including QT prolongation and ventricular arrhythmias. Seek immediate medical attention for fainting, palpitations, or an unusually fast or irregular heartbeat.
7. Is ANGORAB-DSR a prescription medicine?
Yes. ANGORAB-DSR should be used under the supervision of a qualified healthcare professional. The doctor can determine whether the combination, strength, and treatment duration are appropriate for the individual patient, particularly because Domperidone has important dose and cardiovascular safety considerations.
