ZOXFLO-OZ – Ofloxacin & Ornidazole Tablets
ZOXFLO-OZ is a prescription combination tablet containing Ofloxacin 200 mg and Ornidazole 500 mg. Ofloxacin is a fluoroquinolone antibacterial agent, while Ornidazole is a nitroimidazole antimicrobial with activity against susceptible anaerobic organisms and certain protozoa. The combination may be prescribed for selected mixed bacterial and protozoal infections when considered appropriate by a healthcare professional.
Ofloxacin works by interfering with bacterial DNA replication, thereby helping eliminate susceptible bacteria. Ornidazole acts against susceptible anaerobic microorganisms and protozoal infections. Together, the two components may provide antimicrobial coverage in selected gastrointestinal and other infections involving susceptible organisms. Antibiotics should be used only when clinically indicated and do not treat viral infections such as common cold or influenza.
Composition (Per Tablet)
| Ingredient | Quantity |
|---|---|
| Ofloxacin I.P. | 200 mg |
| Ornidazole I.P. | 500 mg |
Pack Size: 10 × 10 Tablets
Strength: Ofloxacin 200 mg + Ornidazole 500 mg
Dosage Form: Tablet
Category: Prescription Antibacterial & Antiprotozoal Combination
Key Selling Points
- ✅ Dual-antimicrobial combination of Ofloxacin and Ornidazole
- ✅ Ofloxacin 200 mg provides antibacterial activity against susceptible bacteria
- ✅ Ornidazole 500 mg provides activity against susceptible anaerobic organisms and protozoa
- ✅ May be prescribed for selected mixed bacterial and protozoal infections
- ✅ Convenient tablet dosage form
- ✅ Available in a practical 10 × 10 tablet pack
Benefits of ZOXFLO-OZ
- Helps treat susceptible bacterial infections when prescribed by a healthcare professional
- Provides antimicrobial activity against susceptible anaerobic organisms through Ornidazole
- Ornidazole is also used against certain protozoal infections
- May provide broad antimicrobial coverage in selected mixed infections
- Convenient fixed-dose combination in a single tablet
How to Take
Take ZOXFLO-OZ exactly as prescribed by your doctor. Swallow the tablet with sufficient water and follow the prescribed dose and treatment duration. Do not stop the antibiotic early simply because symptoms have improved unless your doctor advises you to do so.
Ofloxacin absorption can be reduced by products containing aluminium, calcium, magnesium, iron, zinc, or certain antacids and mineral supplements. These products may need to be taken at a separated time from ofloxacin as directed by your doctor or pharmacist.
Precautions
- For prescription use only.
- Do not use if you have a known allergy to Ofloxacin, other fluoroquinolones, Ornidazole, other nitroimidazoles, or any component of the formulation.
- Inform your doctor if you have a history of tendon disorders, seizures, neurological disorders, kidney or liver disease, or heart rhythm problems.
- Tell your doctor about all prescription medicines, antacids, mineral supplements, vitamins, and herbal products you are taking.
- Fluoroquinolones such as Ofloxacin can rarely cause serious tendon, nerve, muscle, joint, or central nervous system adverse effects. Seek medical advice promptly if significant tendon pain/swelling, numbness, tingling, weakness, or severe neurological symptoms occur.
- Ornidazole can cause gastrointestinal and neurological adverse effects, and rare cases of liver injury have been reported. Seek medical attention for significant jaundice, dark urine, severe abdominal symptoms, or unusual neurological symptoms.
- Use during pregnancy or breastfeeding only after consultation with a qualified healthcare professional.
- Do not use antibiotics for viral infections unless a bacterial infection has also been diagnosed or is strongly suspected.
Frequently Asked Questions (FAQs)
1. What is ZOXFLO-OZ used for?
ZOXFLO-OZ may be prescribed for selected bacterial and protozoal infections, particularly where susceptible bacteria and anaerobic or protozoal organisms are involved. The exact indication should be determined by a healthcare professional based on the suspected or confirmed infection.
2. What does ZOXFLO-OZ contain?
Each tablet contains Ofloxacin 200 mg and Ornidazole 500 mg, as shown on the product packaging.
3. How does ZOXFLO-OZ work?
Ofloxacin is a fluoroquinolone antibacterial medicine that acts against susceptible bacteria by interfering with bacterial DNA replication. Ornidazole is a nitroimidazole antimicrobial used against susceptible anaerobic bacteria and certain protozoal infections.
4. Can ZOXFLO-OZ be taken with other medicines?
ZOXFLO-OZ can interact with certain medicines and supplements. In particular, antacids or supplements containing aluminium, calcium, magnesium, iron, or zinc can affect the absorption of Ofloxacin. Tell your doctor or pharmacist about all medicines and supplements you are taking before starting treatment.
5. Can ZOXFLO-OZ be used for diarrhoea?
It should not be taken routinely for every episode of diarrhoea. Some diarrhoeal illnesses are viral or self-limiting and do not require antibiotics. ZOXFLO-OZ should be used for diarrhoeal or gastrointestinal infections only when a healthcare professional considers antimicrobial treatment appropriate.
6. What are the possible side effects?
Possible side effects may include nausea, vomiting, abdominal discomfort, diarrhoea, dizziness, headache, or altered taste. Ofloxacin and other fluoroquinolones can also cause uncommon but potentially serious tendon, nerve, muscle, joint, and central nervous system reactions. Ornidazole can rarely be associated with neurological effects or liver injury.
7. Is ZOXFLO-OZ a prescription medicine?
Yes. ZOXFLO-OZ should be used under the supervision of a qualified healthcare professional. The doctor can determine whether antibiotic treatment is necessary and select the appropriate medicine, dose, and duration for the infection.
