Composition (Each tablet contains):
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Naproxen Sodium USP – 500 mg
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Domperidone Maleate I.P. (eq. to Domperidone) – 10 mg
🩺 Product Description:
SWITNAP-D 500 is a combination of a non-steroidal anti-inflammatory drug (NSAID) – Naproxen Sodium and a prokinetic agent – Domperidone, used primarily in the treatment of migraine headaches, musculoskeletal pain, and gastric discomfort associated with NSAID therapy. This dual-action formulation relieves pain and inflammation while also managing nausea and gastric side effects.
💊 Uses:
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Treatment of acute migraine attacks
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Relief of headache with nausea or vomiting
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Menstrual pain (dysmenorrhea)
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Musculoskeletal pain (back pain, sprains, arthritis)
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Pain and inflammation with accompanying gastric discomfort
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Fever with nausea
💡 Benefits:
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Naproxen Sodium is a powerful NSAID that reduces inflammation, pain, and fever by inhibiting prostaglandin synthesis.
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Domperidone prevents nausea, bloating, and vomiting commonly associated with migraine or NSAID intake.
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Provides faster relief in migraines by addressing both headache and nausea simultaneously.
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Reduces gastric side effects of NSAIDs by enhancing gastric motility.
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Enhances patient compliance in conditions involving both pain and digestive upset.
🧭 Indications:
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Migraine with or without aura
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Tension headache with nausea
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Postoperative pain with gastric distress
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Gastro-intestinal discomfort due to NSAIDs
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Fever and flu-like symptoms with gastric issues
📌 Dosage:
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Adults: One tablet twice daily after meals or as prescribed by the physician.
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Do not crush or chew.
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Maximum daily dose of Naproxen: 1000 mg (unless otherwise prescribed).
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Duration: Short-term use recommended unless advised for extended therapy.
⚠️ Side Effects:
Common side effects may include:
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Gastric irritation or heartburn
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Dry mouth
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Headache or dizziness
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Constipation or diarrhea
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Drowsiness or fatigue
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Rare: Allergic rash, increased liver enzymes
Seek medical attention if severe allergic reactions, black/tarry stools, or persistent abdominal pain occurs.
🔄 Drug Interactions:
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Antacids & H2 blockers: May reduce Domperidone’s efficacy.
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Anticoagulants (e.g., Warfarin): Increased risk of bleeding with Naproxen.
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Antifungals (Ketoconazole, Fluconazole): May increase Domperidone levels.
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SSRIs, corticosteroids, lithium – Use with caution.
Always consult a physician before combining medications.
🚫 Precautions & Warnings:
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Avoid in patients with peptic ulcers, severe hepatic or renal impairment.
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Not recommended in pregnancy or lactation unless prescribed.
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Use cautiously in elderly patients or those with cardiac conditions.
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Not for children under 12 years.
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Avoid alcohol; it may worsen gastric irritation.
